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Examination of translational biomarkers in clinical samples has the potential to elucidate mechanisms of drug toxicity that have not been previously identified

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72 TrivediA.SinghN.BhatS

This "builds over time" narrative is community-reported and aligns loosely with the synaptogenesis framing, but it is anecdote layered on a mechanism story whose foundational papers were retracted

Int Res J Gastroenterol Hepatol 6(1):3039

By inhibiting cyclooxygenase (COX) enzymes, NSAIDs cause a decrease in the synthesis of prostaglandins that stimulate production of protective mucus and acid-buffering bicarbonate in the digestive tract