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CORRESPONDING AUTHOR: Olivia Avidan MD Department of Internal Medicine Warren Alpert Medical School of Brown University Rhode Island Hospital Providence, RI 02903 Email: [email protected]

In immune-mediated diseases such as GVHD and RA, MSCs modulate T-cell polarization and suppress proinflammatory cytokines and Treg expansion

Jao, S.-C

Yet -hydroxybutyrate suppresses NLRP3 inflammasome activation, and may ameliorate the pro-inflammatory effect [53]

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