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Results take a minimum 3 months 1 year to appear

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Contrary to the inflammatory IFN-- and IL-17-producing Th1 and Th17 cells, Tregs produce immuno-modulatory factors (retinoic acid, IL-10, and transforming growth factor beta (TGF-)), which attenuate the maturation and antigen-presenting properties of ocular DCs, prevent the generation of CD4+Th1 and Th17 lymphocytes in eye-draining lymph nodes, and inhibit the production of inflammatory cytokines (TNF- and IL-1) and Th1- and Th17-attracting chemokines (CXCL9, CXCL10, CCL-20) in N1 neutrophils and M1 macrophages, crucially contributing to the creation of anti-inflammatory microenvironments in the eyes of DED patients [56]

This has to be corrected adding / transplanting part of the extracted fat

Int J Mol Sci 2019;20:1676

GBD 2019 Stroke Collaborators
