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The peptide has shown a generally favorable safety profile, with most adverse events being mild and transient

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AOD-9604 operates through the beta-3 adrenergic pathway independent of the IGF-1 axis and GHRH pathway, making it a clean independent variable alongside IGF-1 LR3 or GHRH analogues like CJC-1295 and tesamorelin in multi-compound research designs

It inhibits nicotinamide N-methyltransferase (NNMT), an enzyme that when overactive, consumes excessive NAD+ and impairs cellular energy metabolism

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