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Therefore, both oxidative stress and a loss of GSH are events known to induce the Nrf2 activity, as shown by the increase of its nuclear level in neurons contained in substantia nigra of the postmortem brain of AD patients, as well as by the presence aberrant of Keap1 in Lewy bodies [75,76]

10.1161/CIRCRESAHA.120.317976 32 CaturanoA.GalieroR.RoccoM.TagliaferriG.PiacevoleA.NiloD.et al (2024)

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