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Oncological safety is particularly unresolved: BPC-157 promotes angiogenesis and cell proliferation, the question of whether long-term use could stimulate abnormal cell growth or impair tumor immune surveillance has not been studied

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A study by Melenovsk et al (78) showed that administration of heme arginate restored heme binding, improved tetramer formation and enhanced catalytic activity of the CBS enzyme in several B6-resistant mutants

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