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Freeze-thaw: Avoid repeated freeze-thaw cycles of the reconstituted solution

ROS such as hydrogen peroxide (H 2 O 2 ), superoxide radical (O 2 ), hydroxyl radical (OH ) and singlet oxygen ( 1 O 2 ), that are produced due to excitation or incomplete reduction of molecular oxygen are harmful byproducts of normal cellular metabolism in aerobic organisms (Mittler et al., 2011)

doi: 10.1016/j.cell.2012.07.017 11 CuiH

S1a) GSH concentrations changed by mito GCL expression

Rhee SD, Kim CH, Park JS, Jung WH, Park SB, Kim HY, Bae GH, Kim TJ, Kim KY (2012) Carbenoxolone prevents the development of fatty liver in C57BL/6-Lep ob/ob mice via the inhibition of sterol regulatory element binding protein-1c activity and apoptosis

doi: 10.1016/S2589-7500(23)00056-0 185 DiexerSKleeBGottschickCXuCBrodaAPurschkeOet al