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Description
The gene encoding GS was cloned in 1995 (Huang et al., 1995) but its transcriptional regulation has only been characterized recently after cloning of the rat and human GS promoters (Yang et al., 2002

The mobile phase A was 97% water and 3% ACN (20 mM NH 4 Ac, 15 mM NH 4 OH, pH = 9.0), and the mobile phase B was 100% ACN

Collectively, these approaches underscore the versatility of TfR1 as a gateway for CNS drug delivery, offering a promising framework for overcoming BBB constraints and enhancing therapeutic precision in neuro-oncology

doi: 10.1097/00004872-200107000-00008

Research indicates that superfluous iron accumulation in the brains basal ganglia may accelerate disease progression (Snchez-Castaeda et al., 2013

Warnings & Precautions
