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Special Precautions Certain groups need to take extra care when considering acetyl-L-carnitine supplementation: Pregnant and breastfeeding women should avoid this supplement due to insufficient safety data Individuals with hypothyroidism may experience worsened symptoms, as acetyl-L-carnitine can interfere with thyroid hormone action People with seizure disorders should consult their doctor, as the supplement may increase seizure risk Those scheduled for surgery should stop taking it at least two weeks beforehand Interactions With Medications Acetyl-L-carnitine can interact with several medications, potentially altering their effectiveness

Mol Nutr Food Res 62:1701069

Am J Clin Nutr 94:938944 Yamada M, Kuroda H, Shimoyama S, Ito R, Sugama Y, Sato K, Yamauchi N, Horiguchi H, Nakamura H, Hamaguchi K, Abe T, Fujii S, Maeda M, Kato J (2016) Efficacy of levocarnitine for tyrosine kinase inhibitor-induced painful muscle cramps in patients with chronic myelogenous leukemia

The non-parametric KruskalWallis test and Duncans multiple range test was used to identify differences between each group

Parkinsonism Relat Disord

Yamazaki Y, Shinohara M, Yamazaki A, Ren Y, Asmann YW, Kanekiyo T, et al
