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Resveratrol attenuates 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated induction of myeloid-derived suppressor cells (MDSC) and their functions
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, poly ADP ribose polymerase [PARP]), together leading to an increase in the NADH/NAD + ratio and promoting ROS production by mitochondrial respiratory complex I due to NADH overload, eventually resulting in reductive stress (38, 105, 107)
Its a sophisticated approach
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