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We also noticed that a lipase brummer ( bmm ) was upregulated in the tissue, which implied altered lipid metabolism in the flies fed the MetR diet for four weeks

[DOI] [PubMed] [Google Scholar] 39.Biewenga WJ, Rijnberk A, Mol JA

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Curcumin, Apigenin, Quercetin inhibits PI3K activity and Akt phosphorylation (Aliyari et al., 2025), resveratrol, found in grapes and red wine, reduces cell migration and invasion, EGCG, the main bioactive component of green tea, downregulates Akt phosphorylation, inhibiting cell proliferation and inflammation (Mokra et al., 2022)

Oleanolic acid alleviating ischemia-reperfusion injury in rat severe steatotic liver via KEAP1/NRF2/ARE