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Naturally occurring missense MRGPRX2 variants display loss of function phenotype for mast cell degranulation in response to substance p, hemokinin-1, human beta-defensin-3, and icatibant
Ras oncoprotein induces CD44 cleavage through phosphoinositide 3-OH kinase and the rho family of small G proteins
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On the 7th day of doxycycline treatment the patients condition deteriorated: a low-grade fever occurred, and severe arthralgias with intense hip, ankle and cervical spine pain and myalgias developed, the authors explain
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There is evidence that the dopamine system also contributes to cognitive and negative symptoms
