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Prior to eventual internalization by distant immune cells, the formation of MVs, which also contain important immune-cell receptors and inhibitory complement receptors, may contribute to an immune or tolerogenic microenvironment for MM cells in the bone marrow (BM) niche [25] [26]

The RP is the major side effect of thoracic radiotherapy in lung and breast cancer patients [61, 62]

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In AUC-SV analysis,runs were carried out at 50,000 r.p.m