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The Aminoglycoside Antibiotic Dihydrostreptomycin Rapidly Enters Mouse Outer Hair Cells through the Mechano-Electrical Transducer Channels

Chelation Therapy DMPS: Used in weekly IV form to remove heavy metals like lead, the dose isnt specified

doi: 10.1016/j.exer.2013.10.024

Indeed, the main targets for mitochondria-generated ROS are mitochondrial permeability transition pore (MPTP), poly (ADP-ribose) polymerase (PARP), and mtDNA ( Other oxidant sources arise from NADPH oxidase, present in astrocytes, microglia and neurons, while NOS inhibition has shown neuroprotective effects ( In the pathogenesis of neurodegeneration, many processes are included, such as protein misfolding and aggregation, abnormal kinase-signaling pathways, neuronal calcium dysregulation, and even impaired synaptic transmission (Takalo et al., 2013)
Available from: Govindaraju V, Young K, Maudsley AA
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