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An update on PPAR activation by cannabinoids
Two main pathways can trigger this process, the intrinsic, also called mitochondrial pathway, when apoptosis is initiated by the internal signals of mitochondrial origin, and the extrinsic when apoptosis is activated by external stimuli [16]
Disruption of these signaling cascades may lead to reduced expression of synapse-associated proteins (Yoshii and Constantine-Paton, 2007)
10.1534/genetics.116.186825 142
They reported decreased cell proliferation, migration and invasion in the studies and significant reduction of tumor growth (Guessous et al., 2010)
Neuron-specific transcriptomic signatures indicate neuroinflammation and altered neuronal activity in ASD temporal cortex
