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Increased protein carbonylation of red blood cell membrane in diabetic retinopathy

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SHR: spontaneously hypertensive rats, Norm: normal rats, Supplementary Figure 2 The results of response permutation tests in the positive ionization mode (A) and negative ionization mode (B) , Supplementary Figure 3 The GSEA results revealing gene enrichment in PPAR signaling pathway (A) and fatty acid degradation (B) , Supplementary Figure 4 (A) Cell viability was measured by CCK8 reagents under different concentrations of Ang II in RAOECs

It plays a critical role in: Cellular energy production DNA repair Brain function and memory Metabolism and fat burning Healthy aging and longevity As we age, NAD+ levels naturally decline contributing to fatigue, brain fog, slower metabolism, and signs of aging

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The transgenic tomatoes showed high level of flavonols in both the peel and flesh (Bovy et al., 2002)