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[DOI] [PMC free article] [PubMed] [Google Scholar] 130.Berretta M., Rinaldi L., Taibi R., Tralongo P., Fulvi A., Montesarchio V., Madeddu G., Magistri P., Bimonte S., Trov M., et al

The ROS generation was detected with a Leica fluorescence microscope (Leica DM6000B) using Leica LAS X software, and quantitative analysis was performed with ImageJ software (version 1.60

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Mutations in these genes can lead to abnormal protein build-up, oxidative stress, and mitochondrial dysfunction, all of which contribute to Parkinson's disease pathogenesis and neuronal death

Each Chr contained an average of 49,734 SNPs, with Chr 4 and Chr 17 showing the most (124,517) and fewest (20,709) SNPs, respectively (Supplementary Fig