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The sensitivity to reliably determine the concentrations of these two amino acids could have been achieved by larger number of scans, although that would also implicate longer MRS acquisition times, as well as longer time under isoflurane anesthesia

Another study provided compelling evidence for the role of Nrf2 as a tumour suppressor, leading to the idea of targeting Nrf2 activators for cancer prevention [102]

Peptides 62, 67136 (2014)

Accordingly, ROS such as the superoxide anion production originates from the Complex I and III, and can damage proteins, lipids or nucleic acids within the mitochondria and cell (Hadrava Vanova et al., 2020)

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[ 324 ] Further research should clarify BACH1's regulatory mechanisms and interactions with metabolismrelated molecules to assess its potential in NAFLD therapy