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Considering the absence of a consensus on diagnostic methods, screening criteria, and treatment for vitamin B12 deficiency in patients with T2D receiving metformin, this narrative review had the following aims: (1) Discuss the diagnostic criteria for vitamin B12 deficiency and the utility of vitamin B12 biomarkers

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[3] [4] This metabolic involvement has led some to speculate about a connection between B12 and energy or fat metabolism a claim that warrants careful scrutiny

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