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The few studies that matched cases with controls did not use a paired method of analysis such as McNemar's test which biases the results towards null

[DOI] [PMC free article] [PubMed] [Google Scholar] 132.Begriche K., Igoudjil A., Pessayre D., Fromenty B

GHK-Cu, a naturally occurring copper peptide, has been studied for its potential effects on visible skin and scalp rejuvenation

Reproducibility statistics used were as follows: coefficient of variation (CV, 77%, 10/13), the intraclass correlation coefficient (ICC, 31%, 4/13) and Pearsons correlation coefficient ( r , 15%, 2/13) (Table 1