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First of all, GSSG may activate the SAPK/MAPK pathway, leading to cell apoptosis

Exposure to ambient moisture (e.g., from repeatedly opening a vial in a humid environment, or from a vial seal failure) introduces water that can degrade the peptide

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[DOI] [PubMed] [Google Scholar] 279.Makhoba XH, Viegas C, Jr, Mosa RA, Viegas FPD, Pooe OJ

Serious nerve damage that lasts a year or longer may not go away