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It is noteworthy, that when the inflammatory insult is removed the young mice are able to fully regain bone density and length 5 weeks later [62]

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Resolution of Dimerization A possible resolution to the dimerization problem, to make the analogues suitable for use in the development of a stable formulation at about neutral pH, could be either removal of the disulfide bridge between Cys2 and Cys7, or replacement of the labile disulfide bridge between positions 2 and 7 with a more chemically stable bond

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