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Translational Breast Cancer Research 2022;3:2

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A deficiency can also cause a condition called megaloblastic anemia which creates larger, immature, and abnormal red blood cells and leads to impaired DNA synthesis

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Medications such as histamine 2 receptor antagonists and proton pump inhibitors (PPIs) (lansoprazole, omeprazole, and esomeprazole) that suppress gastric acid may lower total serum B12 levels by impairing the release of B12 from food (Damodharan et al., 2021

Low dose, slow increase
