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In this specific subgroup, response rates are substantially lower than those reported in unselected diabetic populations and frequently fall below 50%, reflecting the reliance of PDE5-Is on preserved nitrergic signalling and intact neurovascular coupling [43,44]

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European Centre for Disease Prevention and Control (ECDC) Antimicrobial Consumption in the EU/EEA (ESAC-Net) Annual Epidemiological Report 2022 (ECDC, 2023)
482 Patients who receive HD may be at risk of the development of carnitine deficiency as a result of loss of carnitine during the dialysis procedure, in addition to possible reductions in dietary intake and endogenous synthesis

Legal issues In the EU, dietary supplements containing L-carnitine are regulated as foods

Metabolomic evidence further supports a synergistic effect of CIT when combined with HIIT in older adults with obesity
