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The glutamate-induced release was dependent on activation of phospholipase C (PLC) and inositol-3-phosphate receptor (IP3-R) as well as on calcium release from internal calcium stores (Jean et al

Kidney: Patients with kidney disorders should use cautiously under medical supervision

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One in four contained an active drug not mentioned at all

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SS-31 reduces tubular cell apoptosis (cells dying from energy failure), reduces fibrosis (scarring that progressively destroys kidney function), and preserves mitochondrial structure in the proximal tubules