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These findings are supported by gene expression data indicating upregulation of lipolytic markers and 3-adrenergic receptor transcripts

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Several generations of mTORC1 inhibitors have been developed: rapamycin and derivatives (rapalogs), kinase inhibitors including sapanisertib (13), and bi-steric mTORC1-selective inhibitors (14)

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Microbial metabolites have an effect on inflammation and carcinogenesis (136)

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