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doi: 10.1016/j.biopha.2017.08.009

[9] [2] According to NICE guidance, patients with confirmed B12 deficiency and neurological involvement typically require more frequent initial dosing (alternate-day injections) until symptom improvement occurs

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[116] conducted research to see if delivering insulin into the brain of people with Alzheimers disease or amnestic moderate cognitive impairment (MCI) would improve memory without increasing plasma insulin levels

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