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Future Direction and Call to Action The current evidence gap presents an opportunity for orthopaedic investigators to establish high-quality prospective registries evaluating peptide exposure in real-world musculoskeletal populations

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For sciatica caused by disc herniation or spinal stenosis, decompression creates a negative pressure environment inside the disc that can allow herniated material to retract and promote nutrient and oxygen flow to damaged discs

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This treatment may be best in patients who have had known injury to the anterior segment, and who experience continued photo-oculodynia despite complete resolution of the injury

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