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ChemSoc Rev 2008;37:1896-1908

Inhibition of autophagy at a late stage enhances imatinib-induced cytotoxicity in human malignant glioma cells

Originally developed in the 1980s through groundbreaking research identifying the active fragment of naturally occurring GHRH, this 29-amino acid peptide has been investigated in over 50 published studies examining its ability to stimulate endogenous growth hormone secretion

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R., Dimitrijevic, N

However, inconsistent effects on clinical symptoms across trials, heterogeneous dosing schedules, and methodological limitations (including small sample sizes and variable baseline vitamin D status) mean that the overall evidence for routine vitamin D use in endometriosis remains suggestive rather than definitive
