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Because the symptoms are easy to blame on stress or a busy schedule, many people live with low B12 for months before they connect the dots

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Vitamin B 12 -responsive severe leukoencephalopathy and autonomic dysfunction in a patient with normal serum B 12 levels J Neurol Neurosurg Psychiatry 2010;81:1369-71

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as a key regulator of mitochondrial biogenesis, PGC1 enhances mitochondrial function in myoblasts, supplies sufficient energy for differentiation, and regulates the transcription of myogenic genes to accelerate myotube maturation
