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Caribbean Natural Resources Institute, Barataria, Trinidad and Tobago

An increase in total mTOR levels without changes in its phosphorylation status has been previously reported [46]

Finally, we outline intervention strategies targeting tumor metabolism, aiming to provide a theoretical foundation and translational directions for the development of novel anticancer therapies

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We also tested octanoate, which has been previously shown to promote histone acetylation 30 and found that octanoate also increased histone acetylation and acetyl-CoA abundance in the DKO cells, though did not rescue proliferation (Supplemental Figure 4G, H
