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It was demonstrated that the inhibition of Drp1 activity resulted in a reduction of cell death, as observed in studies where mutant SOD1 or TDP-43 were introduced into the system (Nemtsova et al

In summary, the inflamed colonic and ileal epithelia from CD patients have a dysregulation of both the pore and the leak pathway

Ippen M, Ippen H

Both peptides possess antimicrobial activities against Gram-negative and Gram-positive bacteria, eNAP-2 acts additionally as an inhibitor of microbial proteases [34]

The G6PD deficiency is produced by different genetic mechanisms such as deletions, precise mutations and substitutions that affect the transcription, process or primary enzyme structure, which functionally results in a decrease of the enzymatic activity or loss of affinity by the substrate

Goyns, M