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This particular molecule has been synthesized to stop or limit the action of the NNMT enzyme (N-methyltransferase), which is involved in a series of biochemical reactions in the body, one of its main functions related to the metabolism of nicotinamide (a form of vitamin B3)

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Here, through a proteomic screen of serum from AQP4-IgG-positive NMOSD patients and a control cohort, we observed a significant downregulation of Insulin-like growth factor 2 (IGF-2) in the serum of AQP4-IgG-positive NMOSD patients and correlated with disease severity

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Because of this, B vitamins are generally nontoxic, with very little risk of causing harm