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these effects often pass within 30 minutes

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[DOI] [PubMed] [Google Scholar] 5.Sikiric P., Seiwerth S., Rucman R., Kolenc D., Vuletic L.B., Drmic D., Grgic T., Strbe S., Zukanovic G., Crvenkovic D., et al

It is known that by 1 week of cuprizone administration, microglia are activated in the corpus callosum 23 , with astrocytes showing morphological changes as early as 1 week and increasing in density by 3 weeks 24