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Phenome-based approach identifies RIC1-linked Mendelian syndrome through zebrafish models, biobank associations and clinical studies

2026 Apr 30;189(9):2648-2662.e19

A recent chapter in epigenetics is represented by microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) which regulate gene expression
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Selenoproteins appear to limit tumor development during the initiation phase by protecting cells from oxidative DNA damage, but they may instead promote the growth of tumor cells that have already formed and lower the likelihood that patients will survive

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