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The symptoms are closely linked to the various physiological functions of histamine in the body, affecting the skin (e.g., redness, rash, urticaria, pruritus, edema and local inflammation), the gastrointestinal tract (e.g., nausea, vomiting and diarrhea) and the hemodynamic (hypotension) and neurological (e.g., headache, palpitations and tingling) bodily functions [1,41]

Even if youre not in the danger zone, a clinical study published in the Cochrane Library has noted that B12 plays a significant role in preventing neurological decline and maintaining metabolic health

doi: 10.3390/nu12102983 209

Gesundheitsvorteile von Cestfilo: L-Glutathion enthlt natrliche Antioxidantien, die nachweislich Ihr Immunsystem strken und dabei helfen, freie Radikale aus dem Krper zu entgiften

As a result, the skin loses its luster and becomes bland

A report from the Framingham Offspring Study of 2,999 adults found the following average daily B12 intakes, including fortified foods and supplements (Tucker, 2000): Age 26-49: 8.9 g Age 50-64: 8.7 g Age 65-83: 8.5 g A 2015-2016 National Health and Nutrition Examination Survey of over 4,500 adults 60 years and older found the following average daily B12 intakes (USDA NHANES, 2019): Male non-supplement users (68% of men): 4.5 g Male supplement users: 5.3 g from food plus 326 g from supplements Female non-supplement users (63% of women): 3.6 g Female supplement users: 3.8 g from food plus 520 g from supplements European Food Safety Authoritys Recommendations In 2015, the EFSA released recommendations for B12 intake across Europe