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Recent integrative models of endocrineimmune interaction have emphasized the importance of considering cortisol and DHEAS not as independent variables, but as components of a coordinated adaptive system in which their dynamic balance reflects the organisms capacity to maintain metabolic and inflammatory homeostasis

So not something within the ovary or a lack of the pituitary to make LH or FSH, but a deficit of the hypothalamus to promote LH and FSH and the downstream hormones, testosterone and estrogen

Cancer Cell 20 , 606619 (2011)

1988 Jun;24(2):162-72

Ramet ME, Ramet M, Lu Q, Nickerson M, Savolainen MJ, Malzone A, Karas RH

Kurniadi I, Tabri F, Madjid A, Anwar AI, Widita W