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Origlia N, Migliori M, Panichi V, Filippi C, Bertelli A, Carpi A, Giovannini L: Protective effect of L-propionylcarnitine in chronic cyclosporine-a induced nephrotoxicity

The studies that achieved improvements in high-intensity (80% O 2 max ) exercise performance used acute doses of 3 to 4 g of l-C or GPL-C ingested between 60 and 90 min before exercise and chronic doses of 2 to 2.72 g/day of l-C for longer periods up to 9 to 24 weeks

TMAO synergizes with LPS to enhance the activation of NF-B in DCs and macrophages, increase the production of pro-inflammatory cytokines, and impair the function of Tregs

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