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Pregnant or trying to conceive (higher B vitamin demands, especially folate and B6)

22 , 34 , 44 , 118 Vitamin B 12 therapy reduces oxidative damage and inflammation levels, both systemically and in the central nervous system, especially associated with folate

In force January 1, 2026

Other risk factor is homocysteine (Hcy) accumulation in plasma (Hogervorst et al., 2002

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Omega-3 fatty acids reduce inflammation in the brain, supporting mental stability