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Figure 5 Table 3 Pearsons partial correlations among four variables

168 SimonneauC.LeclercqB.MougelA.AdriaenssensE.PaquetC.RaibautL.et al (2015)

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In addition, luteolin can dose-dependently regulate the OS markers (catalase (CAT), nuclear factor erythroid 2-related factor 2 (Nrf2), SOD, and MDA) and proinflammatory cytokines (TNF-, IL-1, and IL-6) in the hippocampus cortex (HPC) and PFC of animals to treat depression [63]

Clinically, OA management predominantly focuses on symptom relief and surgical intervention, underscoring the urgent need to explore its underlying mechanisms and identify new therapeutic targets (Hunter et al., 2020