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Those who had the greatest percent change in that ratio also had a greater percent change in their levels of glutathione in their brain

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Indeed, when the effect of 2APB on drug metabolism was evaluated, it was discovered that 2APB is a P450 inhibitor as directly shown in vitro and observed in vivo when the protection correlated with inhibition of protein adduct formation [155]

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To resemble this ratio, we performed differential scanning calorimetry (DSC) to study the interaction of A 140 in the presence of model membranes composed of large unilamellar vesicles (LUV) DMPC:DMPS 3:1