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C.MusiekE

Physical and chemical instability, quick metabolism, BBB crossing, low bioavailability, and decreased water solubility are some of the issues and limitations that natural products and isolated chemical compounds come with and can affect their therapeutic efficacy [215]

reported that glutamate-induced neurotoxicity in PC-12 cells was evaluated

The role of lipid membranes in -syn pathology: the impact of mitochondrial membranes Alterations in protein processing and cellular homeostasis profoundly affect the conformational behavior of -syn and promote its aggregation into neurotoxic assemblies [24, 63, 66, 73, 94, 98, 112, 122, 139, 290]

10.1038/383826a0

Biomarkers of oxidative stress in erythrocytes as a function of human age
