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In America, there has been a 33 percent increase in asthma in the last 10 years

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After major surgery, patients often exhibit transient T-cell immunosuppression for example, reduced IL-2 production and proliferative anergy in response to mitogens, contributing to increased infection risk in the week following surgery ( via inhibitory receptors like PD-1 being upregulated in the stress environment

doi: 10.3389/fnins.2023.1301066