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This can include drug metabolites, heavy metals, pesticides/herbicides, xenoestrogens like BPA, alcohol, and other toxic chemicals

Furthermore, as a specific cargo receptor involved in autophagy, NCOA4 bound ferritin and delivered it to lysosomes for degradation, resulting in the release of free iron and an increase in the level of the LIP in cells (Fig

Excessive sweating can be caused by an overactive sympathetic nervous system

Orthostatic intolerance in long-haul COVID after SARS-CoV-2: a case-control comparison with post-EBV and insidious-onset myalgic encephalomyelitis/chronic fatigue syndrome patients

Though this architecture maps triggers to endotypes, definitive associations remain elusive due to intricate underlying biology, where triggers initiate or exacerbate disease but do not dictate endotype