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Meloni, T
Furthermore, to sustain the conversion of pyruvate to acetyl-CoA and its entry in the TCA cycle, due to the lack of glutamate induced by GLS1 knockdown, it implies the activation of other metabolic pathways
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After treatment with various concentrations of Cys, GSH, and MIX (Cys:GSH = 3:1) for 24 h, the cell viability was measured using a WST-8 assay kit (BIOMAX) as per the manufacturers instructions
doi: 10.1172/JCI200421146
This is no coincidence
