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Written informed consent was obtained from the owners for the participation of their animals in this study

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Since then, the finding of high HPHPA values in autism has been confirmed by research groups in China (Xiong, Liu, Wang, Zeng, and Peng 2016) Turkey (Keli , Gken, Bulu, and Terzi, 2014), and Italy (Noto et al., 2014)

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It is generated within endothelial cells through the conversion of L-arginine to L-citrulline by the enzyme eNOS