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Description
7.2 Integration of multi-omics approaches We proposed that future research should combine metagenomics, metabolomics, and transcriptomics to better elucidate the complex interactions between gut microbiota alterations and hepatic metabolic dysfunction in cadmium-induced liver injury

CCI induced significant thermal hyperalgesia and mechanical allodynia from postoperative day 3 to day 21, which was accompanied by significant downregulation of GLT-1 expression in the spinal cord

Key immunomodulatory actions include enhanced phagocytic activity of peripheral leukocytes, upregulated secretion of immunoglobulins (IgA, IgG, and IgM), and increased production of cytokines such as interleukins, TNF-, and interferon- (IFN-) (488)

These strategies not only enhance bioavailability but also facilitate the co-delivery of curcumin with chemotherapeutics, as seen in nanomicelles loaded with doxorubicin and curcumin, which effectively reverse MDR in lung cancer [80]

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32% of 74 patients in the BE HEARD II trial) and with bimekizumab every 4 weeks versus placebo in the BE HEARD II trial (54% of 144 patients vs
