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MSCs and EXOs transplantation helped to heal the endometrium and promote female fertility, most likely by inhibiting extensive fibrotic and inflammatory reactions, increasing endometrial cell division, and regulating mediators associated with endometrial receptivity

The notable exception in this group is thymosin alpha 1, approved in more than 35 countries (as Zadaxin) for hepatitis B and C and as immune support in cancer care, with a substantial human trial base

In addition, glutamate shows the highest absolute increase in concentration along lactation, increasing from ~1.25 to 1.75 mM from month 1 to 6 of lactation (35)

Prieto et al

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In bacteria this has been implicated as one reason why copper induced protein aggregation is significantly intensified during hypoxia (Zuily et al., 2022), a possibility that could also apply for mammalian cells
