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Gut-brain axis: A matter of concern in neuropsychiatric disorders
METAOD006 was a 24-week, randomized, double-blind, placebo-controlled, multicenter Phase 2b study that enrolled around 500 clinically obese adults, randomized to daily oral doses of AOD-9604 (0.25, 0.5, or 1 mg) or placebo, on a background diet-and-exercise regimen
Individual response varies substantially based on genetics, body composition, activity level, and dozens of other factors
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A condition that can manifest with neurologic, psychiatric, and hematologic disorders is vitamin B12 deficiency
The 4-week minimum at each dose level is not arbitrary
