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Gahan 2 Author information Abstract DNA methylation is essential for regulating tissue-specific gene expression, genomic imprinting, X chromosome inactivation and retroviral element silencing

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337,338 It has been shown to prevent the progression of age-dependent intervertebral disc degeneration, 339 reduce intestinal SnCs and excessive inflammation in aged mice, 340 and effectively induce apoptosis, thereby eliminating SnCs and the SASP burden in adipose tissue

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PLoS On 9(11):e111649